Lorenzo's Oil

Lorenzo's Oil is a 1992 drama film directed and co-written by George Miller. It is based on the true story of Augusto and Michaela Odone (played by Nick Nolte and Susan Sarandon), parents who search for a cure for their son Lorenzo's (played by Zack O'Malley Greenburg) adrenoleukodystrophy (ALD), leading to the development of Lorenzo's oil. The film was shot in Pittsburgh, Pennsylvania, primarily from September 1991 to February 1992. It had a limited release in North America on December 30, 1992, with a nationwide release on January 15, 1993. Though it was a box office disappointment, grossing $7.2 million against its $30 million budget, the film was generally well received by critics and garnered two nominations at the 65th Academy Awards.